Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995464 | 0.84 | MAPT (0.43) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL6873524 | 0.84 | MAPT (0.43) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL17690042 | 0.82 | MAPT (0.41) | MAPTPOLBKMT2AKDM4ELMNA | |
| SCHEMBL19606600 | 0.76 | LGALS8 (0.32) | LMNATSHR | |
| SCHEMBL15494051 | 0.74 | CYP3A4 (0.36) | LMNATSHR | |
| SCHEMBL12942461 | 0.74 | CYP3A4 (0.36) | LMNATSHR | |
| SCHEMBL15494059 | 0.74 | CYP3A4 (0.36) | LMNATSHR | |
| SCHEMBL6876833 | 0.73 | MAPT (0.43) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8004202 | 0.73 | MAPT (0.43) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL19606620 | 0.72 | KCNH2 (0.37) | LMNAGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464651-B1 | NEW MACROLIDES AND THEIR USE | BASILEA PHARMACEUTICA AG (CH) | 2016-04-20 | — | — | EP | disclosed |