Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004202 | 1.00 | MAPT (0.43) | MAPTPOLBVNN1MMP13SMN1; SMN2 | |
| SCHEMBL17690042 | 0.78 | MAPT (0.41) | MAPTPOLBVNN1SMN1; SMN2KDM4E | |
| SCHEMBL6873524 | 0.77 | MAPT (0.43) | MAPTPOLBVNN1SMN1; SMN2KDM4E | |
| SCHEMBL7995464 | 0.77 | MAPT (0.43) | MAPTPOLBVNN1SMN1; SMN2KDM4E | |
| SCHEMBL8004313 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL8004779 | 0.75 | TSHR (0.30) | TSHR | |
| SCHEMBL7996032 | 0.75 | TSHR (0.30) | TSHR | |
| SCHEMBL12349632 | 0.74 | MAPT (0.49) | MAPTPOLBVNN1MMP13SMN1; SMN2 | |
| SCHEMBL17690155 | 0.73 | MAPT (0.39) | MAPTPOLBMMP13SMN1; SMN2KDM4E | |
| SCHEMBL4375383 | 0.72 | MAPT (0.50) | MAPTPOLBVNN1MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018510-A1 | NEW MACROLIDES AND THEIR USE | BASILEA PHARMACEUTICA AG (CH) | 2011-02-17 | — | — | WO | disclosed |