Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613450 | 0.81 | TAAR1 (0.47) | SMN1; SMN2TDP1TAAR1CYP2C9CYP2C19 | |
| SCHEMBL31374947 | 0.79 | SLC6A4 (0.46) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL4527865 | 0.77 | POLB (0.43) | TAAR1IDO1 | |
| SCHEMBL735823 | 0.77 | OPRL1 (0.56) | ALDH1A1MAOB | |
| SCHEMBL1773425 | 0.76 | GRIN2D (0.48) | SMN1; SMN2 | |
| SCHEMBL25518220 | 0.75 | PNMT (0.46) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL28914545 | 0.75 | TAAR1 (0.52) | SMN1; SMN2TDP1TAAR1IDO1AGXT | |
| SCHEMBL30063439 | 0.75 | TAAR1 (0.52) | SMN1; SMN2TDP1TAAR1IDO1AGXT | |
| SCHEMBL2192474 | 0.75 | OPRL1 (0.54) | ALDH1A1MAOB | |
| SCHEMBL2192517 | 0.75 | OPRL1 (0.54) | ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009421-A1 | GLYCINE TRANSPORTER INHIBITOR | Taisho Pharmaceutical Co., Ltd. (JP) | 2016-04-20 | — | — | EP | disclosed |