SCHEMBL28914545

SCHEMBL28914545

OC1(CCc2cccc(Br)c2)CC1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
OPRM1 P35372 4/20 0.51
OPRL1 P41146 3/20 0.51
OPRD1 P41143 2/20 0.51
OPRK1 P41145 2/20 0.51
KDM1A O60341 2/20 0.42
RCOR1 Q9UKL0 2/20 0.42
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30063439 1.00 TAAR1 (0.52) TAAR1OPRM1OPRL1OPRD1OPRK1
SCHEMBL613450 0.92 TAAR1 (0.47) TAAR1OPRM1OPRL1OPRD1OPRK1
SCHEMBL28026632 0.89 TAAR1 (0.45) TAAR1OPRM1OPRL1OPRD1OPRK1
SCHEMBL20512444 0.77 OPRM1 (0.60) TAAR1OPRM1OPRL1OPRD1OPRK1
SCHEMBL28914563 0.77 OPRM1 (0.69) TAAR1OPRM1OPRL1OPRD1OPRK1
SCHEMBL2407833 0.76 TAAR1 (0.58) TAAR1KDM1ARCOR1IDO1AGXT
SCHEMBL4399626 0.76 TAAR1 (0.74) TAAR1IDO1AGXTSMN1; SMN2TDP1
SCHEMBL17690230 0.75 SMN1; SMN2 (0.45) TAAR1IDO1AGXTSMN1; SMN2TDP1
SCHEMBL27837195 0.75 TAAR1 (0.56) TAAR1KDM1ARCOR1IDO1AGXT
SCHEMBL7008701 0.72 TAAR1 (0.63) TAAR1IDO1AGXTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322100-A Delta, epsilon-alkenyl ketone compound and preparation method and application thereof 南京工业大学 2022-11-11 CN claimed
CN-115322100-A Delta, epsilon-alkenyl ketone compound and preparation method and application thereof 南京工业大学 2022-11-11 CN disclosed