Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548531 | 0.72 | MIF (0.62) | P2RY6MIFCA1CA2ADORA2B | |
| SCHEMBL19403602 | 0.70 | ALDH1A1 (0.42) | HSD17B10AGTR1AGTR2 | |
| Bitoscanate SCHEMBL157128 | 0.69 | MIF (0.72) | P2RY6MIFCA1CA2HSD17B10 | |
| SCHEMBL22064853 | 0.66 | MIF (0.54) | P2RY6MIFCA1CA2ADORA2B | |
| SCHEMBL5725177 | 0.66 | P2RY6 (0.48) | P2RY6MIFCA1CA2ADORA2B | |
| SCHEMBL3414004 | 0.65 | MIF (0.73) | P2RY6MIFCA1CA2HSD17B10 | |
| SCHEMBL21993644 | 0.65 | MIF (0.73) | P2RY6MIFCA1CA2HSD17B10 | |
| SCHEMBL21027661 | 0.63 | P2RY6 (0.50) | P2RY6MIFCA1CA2ADORA2B | |
| SCHEMBL21387144 | 0.63 | ESR1 (0.50) | P2RY6MIFCA1CA2HSD17B10 | |
| SCHEMBL12011022 | 0.63 | P2RY6 (0.50) | P2RY6MIFCA1CA2ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492262-B1 | FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |