Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 5/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.45 |
| ▸ | HRH2 | P25021 | 8/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24589696 | 0.80 | HRH3 (0.40) | LIMK1HRH3HRH2NOS3NOS1 | |
| SCHEMBL12294286 | 0.71 | LIMK1 (0.54) | LIMK1HRH3HRH2NOS3NOS1 | |
| SCHEMBL12288911 | 0.70 | EPAS1 (0.48) | LIMK1 | |
| SCHEMBL10288720 | 0.68 | LIMK1 (0.34) | LIMK1 | |
| SCHEMBL9538574 | 0.66 | HRH3 (0.34) | LIMK1HRH3HRH2 | |
| SCHEMBL9433906 | 0.65 | LIMK1 (0.46) | LIMK1NOS3NOS1NOS2 | |
| SCHEMBL30095833 | 0.65 | LIMK1 (0.46) | LIMK1NOS3NOS1NOS2 | |
| SCHEMBL361602 | 0.65 | LIMK1 (0.46) | LIMK1NOS3NOS1NOS2 | |
| SCHEMBL14280462 | 0.64 | CCR1 (0.40) | HRH3HRH2 | |
| SCHEMBL13686454 | 0.63 | LIMK1 (0.40) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009436-A1 | KINASE INHIBITORS AND METHODS OF USE | Intellikine, LLC (US) | 2016-04-20 | — | — | EP | disclosed |