Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305096 | 0.86 | PDE2A (0.40) | SMN1; SMN2PTGER4PPARAHDAC4HDAC6 | |
| SCHEMBL16305069 | 0.82 | PTGER4 (0.52) | PTGER4PPARAPPARG | |
| SCHEMBL17684652 | 0.81 | RORC (0.44) | PTGER4PPARAPPARG | |
| SCHEMBL16305091 | 0.80 | PTGER4 (0.37) | SMN1; SMN2PTGER4PPARACNR1CNR2 | |
| SCHEMBL17690477 | 0.79 | NR1H4 (0.48) | PTGER4CNR1CNR2PPARG | |
| SCHEMBL17684549 | 0.75 | CCR9 (0.41) | PTGER4 | |
| SCHEMBL16305088 | 0.75 | RORC (0.48) | PTGER4 | |
| SCHEMBL17684432 | 0.74 | KDM4E (0.41) | SMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL20113478 | 0.74 | PTGER4 (0.43) | PTGER4HDAC6GSK3B | |
| SCHEMBL16305136 | 0.74 | PTGER4 (0.51) | PTGER4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-A1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | Kaken Pharmaceutical Co., Ltd. (JP) | 2016-04-20 | — | — | EP | disclosed |