Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.74 |
| ▸ | ADH1A | P07327 | 4/20 | 0.74 |
| ▸ | ADH1C | P00326 | 3/20 | 0.59 |
| ▸ | ADH7 | P40394 | 2/20 | 0.59 |
| ▸ | ADH4 | P08319 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404197 | 1.00 | ADH1B (0.74) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL17690614 | 1.00 | ADH1B (0.74) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL19658308 | 0.86 | ADH1B (1.00) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL115609 | 0.86 | — | — | |
| SCHEMBL21997344 | 0.86 | ADH1B (1.00) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL20678957 | 0.85 | — | — | |
| SCHEMBL18924689 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL4095046 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL9205102 | 0.83 | — | — | |
| Bicarbonate SCHEMBL11031476 | 0.81 | ADH1B (0.78) | ADH1BADH1AADH1CADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707372-B1 | SPIRO-OXINDOLE MDM2 ANTAGONISTS | UNIV MICHIGAN REGENTS (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-2321272-B1 | ORGANIC COMPOUNDS | NABRIVA THERAPEUTICS AG (AT) | 2016-04-20 | — | — | EP | disclosed |