Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769899 | 0.90 | DRD2 (0.57) | DRD2DRD4HSD11B1LMNANPC1 | |
| SCHEMBL770291 | 0.90 | GAA (0.56) | DPP4HSD11B1LMNAGAADPP8 | |
| SCHEMBL770465 | 0.89 | DPP4 (0.45) | TRPV1DRD2DRD4DPP4DPP8 | |
| SCHEMBL770456 | 0.87 | MEN1 (0.55) | DPP4HSD11B1LMNAGAADPP8 | |
| SCHEMBL771171 | 0.87 | HDAC3 (0.51) | DRD2DRD4DPP4HSD11B1LMNA | |
| SCHEMBL770444 | 0.87 | ALDH1A1 (0.51) | TRPV1DPP4LMNAGAACNR1 | |
| SCHEMBL769950 | 0.84 | HRH3 (0.53) | DRD2DRD4HSD11B1LMNA | |
| SCHEMBL770499 | 0.82 | HPGD (0.54) | NPC1RAB9A | |
| SCHEMBL771331 | 0.82 | MAPT (0.57) | GAASMN1; SMN2 | |
| SCHEMBL772521 | 0.79 | HRH3 (0.54) | DPP4F2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |