Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771390 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL772428 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL770601 | 0.84 | EPHX2 (0.47) | DPP4FAPDPP7DRD2DRD4 | |
| SCHEMBL771159 | 0.83 | DPP4 (0.44) | SMN1; SMN2DPP4FAPDPP7DRD2 | |
| SCHEMBL17690740 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2DPP4FAPDPP7NPC1 | |
| SCHEMBL769928 | 0.82 | L3MBTL1 (0.46) | SMN1; SMN2DPP4FAPDPP7NPC1 | |
| SCHEMBL770615 | 0.80 | DRD2 (0.49) | SMN1; SMN2DPP7DRD2DRD4NPC1 | |
| SCHEMBL770313 | 0.79 | MAPT (0.54) | SMN1; SMN2DPP4NPC1RAB9AHPGD | |
| SCHEMBL771370 | 0.79 | HDAC3 (0.49) | DPP4FAPDPP7NPC1RAB9A | |
| SCHEMBL770692 | 0.78 | NPC1 (0.46) | SMN1; SMN2DPP4DRD2DRD4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |