⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435765 | 0.93 | TAAR1 (0.59) | — | |
| SCHEMBL4847978 | 0.91 | TAAR1 (0.57) | — | |
| SCHEMBL3194709 | 0.91 | TAAR1 (0.57) | — | |
| SCHEMBL9436069 | 0.91 | TAAR1 (0.57) | — | |
| SCHEMBL1309426 | 0.86 | — | — | |
| SCHEMBL20146704 | 0.85 | TAAR1 (0.73) | — | |
| SCHEMBL20135772 | 0.85 | TAAR1 (0.73) | — | |
| SCHEMBL6734915 | 0.83 | TAAR1 (0.70) | — | |
| SCHEMBL8571535 | 0.83 | TAAR1 (0.70) | — | |
| SCHEMBL7116263 | 0.83 | TAAR1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081476-A2 | PROCESS FOR PREPARING DULOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-07-10 | — | — | WO | claimed |
| US-9321769-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2016-04-26 | — | — | US | disclosed |
| US-9321769-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2016-04-26 | — | — | US | disclosed |
| US-9321769-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2016-04-26 | — | — | US | disclosed |
| US-9125415-B2 | Thiophene based oligomers as light activated biocides | STC, UNM (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125415-B2 | Thiophene based oligomers as light activated biocides | STC, UNM (US) | 2015-09-08 | — | — | US | disclosed |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2015-08-20 | — | — | US | disclosed |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2015-08-20 | — | — | US | disclosed |
| US-20150232466-A1 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS | FAB PHARMA S.A.S. (FR) | 2015-08-20 | — | — | US | disclosed |
| US-9051321-B2 | Heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA S.A.S. (FR) | 2015-06-09 | — | — | US | disclosed |
| EP-0687265-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-12-20 | — | — | EP | disclosed |
| WO-1995017180-A1 | A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS | NOVO NORDISK A/S (DK) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017185-A1 | A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS | NOVO NORDISK A/S (DK) | 1995-06-29 | — | — | WO | disclosed |
| CN-1028229-C | Heterocyclic compounds containing nitrogen and sulfur, pharmaceutical composition containing same and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1995-04-19 | — | — | CN | disclosed |
| WO-1995005174-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1995-02-23 | — | — | WO | disclosed |
| WO-1995005379-A1 | ANTIPSYCHOTIC METHOD | NOVO NORDISK A/S (DK) | 1995-02-23 | — | — | WO | disclosed |
| US-5376668-A | Cholinergic agents as cognition activators in treatment of Alzheimer*s disease | NOVO NORDISK A/S (DK) | 1994-12-27 | — | — | US | disclosed |
| WO-1994020496-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-09-15 | — | — | WO | disclosed |
| WO-1994020495-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-09-15 | — | — | WO | disclosed |
| CN-1049159-A | The heterogeneous ring compound of new nitrogenous and sulphur, the method that contains the pharmaceutical composition of this compounds and prepare them | RICHTER GEDEON VEGYESZET (HU) | 1991-02-13 | — | — | CN | disclosed |