SCHEMBL17691820

SCHEMBL17691820

c1nc2ccc(-c3ccc4c(ccc5cc(-c6ccc7ncsc7c6)ccc54)c3)cc2s1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.63
APP P05067 1/20 0.48
RIPK1 Q13546 1/20 0.48
TGFBR1 P36897 11/20 0.46
BMPR1A P36894 1/20 0.46
SMAD2 Q15796 1/20 0.46
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HKDC1 Q2TB90 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPK14 Q16539 1/20 0.44
VRK1 Q99986 1/20 0.43
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
FFAR1 O14842 1/20 0.41
PFKFB3 Q16875 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691914 0.94 DYRK1A (0.56) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691852 0.92 DYRK1A (0.55) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691827 0.92 DYRK1A (0.55) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691909 0.91 DYRK1A (0.54) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691933 0.89 DYRK1A (0.56) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691887 0.88 DYRK1A (0.51) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691918 0.88 DYRK1A (0.50) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL31214345 0.87 DYRK1A (0.72) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17691911 0.83 DYRK1A (0.46) DYRK1AAPPRIPK1TGFBR1BMPR1A
SCHEMBL17229095 0.81 DYRK1A (0.57) DYRK1AAPPRIPK1TGFBR1BMPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed