SCHEMBL17692006

SCHEMBL17692006

c1ccc(-c2cc(-c3cc4ccc5ccccc5c4c4ccccc34)cc3ccncc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 3/20 0.57
CYP11B1 P15538 3/20 0.49
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 2/20 0.47
MAPK10 P53779 1/20 0.47
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
RAD52 P43351 1/20 0.43
ALOX5 P09917 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.40
HASPIN Q8TF76 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GPR84 Q9NQS5 1/20 0.39
MPI P34949 1/20 0.39
TDO2 P48775 2/20 0.39
CYP11B2 P19099 2/20 0.38
CYP17A1 P05093 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17692052 0.87 TNF (0.55) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17691885 0.83 TNF (0.60) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692022 0.82 CYP11B1 (0.43) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL20698273 0.82 TNF (0.41) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692002 0.82 TDO2 (0.57) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692189 0.81 TNF (0.61) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL27340445 0.80 CYP11B1 (0.45) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692014 0.80 TDO2 (0.52) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692197 0.79 TNF (0.59) TNFCYP11B1KDM4EALDH1A1MAPT
SCHEMBL17692141 0.78 TNF (0.61) TNFCYP11B1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed