SCHEMBL17692189

SCHEMBL17692189

c1ccc(-c2cc(-c3ccc4c5c(cccc35)-c3cc5ccccc5cc3-4)cc3ccncc23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 3/20 0.61
CYP11B1 P15538 3/20 0.46
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
CASP1 P29466 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 4/20 0.40
HTT P42858 2/20 0.40
POLB P06746 1/20 0.40
RAD52 P43351 1/20 0.40
HASPIN Q8TF76 1/20 0.40
ALOX5 P09917 1/20 0.39
MAPK10 P53779 1/20 0.39
TP53 P04637 1/20 0.38
CASP7 P55210 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17692141 0.94 TNF (0.61) TNFCYP11B1ALDH1A1HPGDTSHR
SCHEMBL17692197 0.88 TNF (0.59) TNFCYP11B1ALDH1A1HPGDTSHR
SCHEMBL17692215 0.88 TNF (0.57) TNFCYP11B1ALDH1A1HPGDKDM4E
SCHEMBL25596111 0.82 ALDH1A1 (0.43) TNFCYP11B1ALDH1A1HPGDTSHR
SCHEMBL17692006 0.81 TNF (0.57) TNFCYP11B1ALDH1A1HPGDKDM4E
SCHEMBL9825900 0.78 TNF (0.73) TNFCYP11B1KDM4EHTTPOLB
SCHEMBL30933417 0.78 TNF (1.00) TNFCYP11B1ALDH1A1HPGDTSHR
SCHEMBL14740148 0.78 TNF (1.00) TNFCYP11B1ALDH1A1HPGDTSHR
SCHEMBL25596048 0.76 ALDH1A1 (0.45) TNFALDH1A1HPGDTSHRMAPK1
SCHEMBL17692159 0.76 TNF (0.43) TNFCYP11B1ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed