SCHEMBL17692017

SCHEMBL17692017

c1ccc(-c2ccnc(-c3ccc4c(ccc5cc(-c6nccc(-c7ccccn7)n6)c6ccccc6c54)c3)n2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 4/20 0.41
KDM4E B2RXH2 5/20 0.38
LMNA P02545 3/20 0.38
TP53 P04637 2/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 2/20 0.38
ALPL P05186 1/20 0.38
HSP90AA1 P07900 1/20 0.38
ALPI P09923 1/20 0.38
ALPG P10696 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691992 0.87 KMT2A (0.41) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17692001 0.86 KDM4E (0.41) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17691903 0.85 NPC1 (0.62) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17691979 0.84 ALDH1A1 (0.39) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17691984 0.81 DHODH (0.41) NPC1RAB9ASMN1; SMN2KDM4ELMNA
SCHEMBL17229049 0.80 NPC1 (0.62) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17692012 0.80 TGFBR1 (0.38) RAB9ASMN1; SMN2KDM4ELMNATP53
SCHEMBL17692016 0.78 KDM4E (0.41) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL17692021 0.78 ERN1 (0.41) NPC1RAB9ALMNATP53ALDH1A1
SCHEMBL17692011 0.76 MAPT (0.37) NPC1RAB9AMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed