Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474677 | 0.93 | KMT2A (0.71) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL27504484 | 0.93 | KMT2A (0.66) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL11602621 | 0.92 | KMT2A (0.64) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL27750481 | 0.89 | KMT2A (0.51) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL28621572 | 0.89 | KMT2A (0.51) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL10725091 | 0.85 | BCL9 (0.52) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL6771959 | 0.84 | KMT2A (0.54) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL28670395 | 0.84 | GAA (0.56) | KMT2ASMN1; SMN2GAABCL9CTNNB1 | |
| SCHEMBL25205316 | 0.84 | GAA (0.49) | KMT2ATDP1SMN1; SMN2HTTGAA | |
| SCHEMBL9836035 | 0.84 | GAA (0.46) | KMT2ATDP1SMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | claimed |
| CN-106232582-A | Aryl and heteroaryl ether compound as ROR gamma modulators | 格兰马克药品股份有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-102985402-A | Tranylcypromine derivatives as inhibitors of histone demethylase LSD1 and/or LSD2 | UNIV ROMA | 2013-03-20 | — | — | CN | disclosed |
| WO-2011061760-A1 | NOVEL ANTITHROMBOTIC AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |
| CN-1161962-A | Sulphonic-acid-amide derivative | KONO PHARMACEUTICAL IND K K (JP) | 1997-10-15 | — | — | CN | disclosed |