Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836028 | 0.86 | GAA (0.46) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL1769204 | 0.84 | KMT2A (0.59) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL27504484 | 0.81 | KMT2A (0.66) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL27474677 | 0.81 | KMT2A (0.71) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL11602621 | 0.80 | KMT2A (0.64) | GAAKMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL472074 | 0.79 | ELANE (0.51) | GAAKMT2ATDP1SMN1; SMN2HTT | |
| SCHEMBL27750481 | 0.77 | KMT2A (0.51) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL28621572 | 0.77 | KMT2A (0.51) | GAACES2CES1KMT2ATDP1 | |
| SCHEMBL28670395 | 0.76 | GAA (0.56) | GAACES2CES1KMT2ASMN1; SMN2 | |
| SCHEMBL25205316 | 0.75 | GAA (0.49) | GAACES2CES1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219154-B1 | FURYL COMPOUNDS, THEIR USE AS FUNGICIDES AND THEIR PREPARATION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-11-13 | — | — | EP | disclosed |
| EP-0219154-A2 | Furyl compounds, their use as fungicides and their preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-22 | — | — | EP | disclosed |