Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611121 | 0.90 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6607338 | 0.88 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL591401 | 0.81 | MGLL (0.59) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6610001 | 0.80 | TP53 (0.51) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6610098 | 0.77 | MGLL (0.47) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6401881 | 0.76 | TSHR (0.47) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL30853659 | 0.76 | MGLL (0.59) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2088984 | 0.76 | MGLL (0.59) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6399505 | 0.76 | MCHR1 (0.47) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6398417 | 0.76 | MCHR1 (0.47) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061760-A1 | NOVEL ANTITHROMBOTIC AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |