Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181000 | 0.76 | BCHE (0.66) | BCHEACHEBACE1MAPTPOLB | |
| SCHEMBL2817383 | 0.75 | NPC1 (0.50) | MAPTPOLBLMNAGAAMEN1 | |
| SCHEMBL1769433 | 0.74 | TSHR (0.47) | ACHEMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL14176144 | 0.74 | ATM (0.49) | BCHEACHEMAPTPOLBLMNA | |
| SCHEMBL2817503 | 0.74 | MAOA (0.52) | SLC6A2SLC6A4SLC6A3ACHEALDH1A1 | |
| SCHEMBL5651590 | 0.73 | GRIN2B (0.61) | BCHEACHEBACE1MAPTPOLB | |
| SCHEMBL3258974 | 0.71 | ALDH1A1 (0.53) | MAPTLMNAALDH1A1HTR1ENPSR1 | |
| SCHEMBL3905346 | 0.71 | HTT (0.46) | SLC6A2SLC6A4SLC6A3MAPTLMNA | |
| SCHEMBL18181888 | 0.70 | POLB (0.67) | BCHEACHEBACE1MAPTPOLB | |
| SCHEMBL3099025 | 0.69 | POLB (0.69) | BCHEACHEBACE1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061760-A1 | NOVEL ANTITHROMBOTIC AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |