Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769462 | 0.90 | F10 (0.48) | OPRM1SIGMAR1GRM2 | |
| SCHEMBL1769216 | 0.84 | CALML3 (0.52) | MAOAMAOB | |
| SCHEMBL1769541 | 0.84 | SIGMAR1 (0.47) | OPRM1SIGMAR1GRM2SLC22A1SLC6A4 | |
| SCHEMBL16809996 | 0.77 | MAOA (0.70) | MAOAMAOBSIGMAR1GRM2 | |
| SCHEMBL12728919 | 0.77 | MAOA (0.70) | MAOAMAOBSIGMAR1GRM2 | |
| SCHEMBL1769446 | 0.75 | MAOB (0.43) | MAOAMAOB | |
| SCHEMBL7313927 | 0.75 | SIGMAR1 (0.56) | MAOAMAOBSIGMAR1 | |
| SCHEMBL7313919 | 0.75 | SIGMAR1 (0.56) | MAOAMAOBSIGMAR1 | |
| SCHEMBL6613011 | 0.74 | MAOA (0.58) | MAOAMAOBGRM2 | |
| SCHEMBL1223003 | 0.74 | GRM2 (0.67) | MAOAMAOBSIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061760-A1 | NOVEL ANTITHROMBOTIC AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |