Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035628 | 0.81 | GRIK2 (0.59) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL6279611 | 0.72 | MAPT (0.55) | KDM4EALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL7942901 | 0.69 | GRIK2 (0.65) | KDM4EALDH1A1MAPTALOX15HPGD | |
| SCHEMBL29565152 | 0.68 | GRIK2 (0.53) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL11658854 | 0.68 | GRIK2 (0.72) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL19275255 | 0.67 | ALDH1A1 (0.77) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL6287191 | 0.67 | PDE4B (0.50) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL6287779 | 0.67 | PDE4B (0.50) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL6286533 | 0.67 | PDE4B (0.50) | KDM4EALDH1A1MAPTGAAALOX15 | |
| SCHEMBL6287258 | 0.67 | PDE4B (0.50) | KDM4EALDH1A1MAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108031-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | HEINRICH-HEINE-UNIVERSITAT DUSSELDORF (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108031-A1 | INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION | RUNX1, ETV6, NPM1 | KDM4E 2323/4885ALDH1A1 4852/4885MAPT 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.