Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PIEZO1 | Q92508 | 12/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695680 | 0.89 | GSK3B (0.56) | TERTGSK3AGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL17695691 | 0.86 | GSK3A (0.71) | TERTGSK3AGSK3BPIEZO1HSD17B10 | |
| SCHEMBL17695696 | 0.86 | GSK3A (0.61) | TERTGSK3AGSK3BPIEZO1HSD17B10 | |
| SCHEMBL17695693 | 0.83 | GSK3A (0.69) | TERTGSK3AGSK3BPIEZO1HSD17B10 | |
| SCHEMBL17695699 | 0.82 | TERT (0.58) | TERTGSK3AGSK3BPIEZO1HSD17B10 | |
| SCHEMBL17695687 | 0.78 | GSK3B (0.69) | TERTGSK3AGSK3BPIEZO1HSD17B10 | |
| SCHEMBL17695697 | 0.77 | GSK3A (0.62) | TERTGSK3AGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL17695679 | 0.75 | GSK3A (0.72) | GSK3AGSK3BHSD17B10MEN1ALDH1A1 | |
| SCHEMBL17695702 | 0.75 | GSK3A (0.71) | GSK3AGSK3BHSD17B10ALDH1A1 | |
| SCHEMBL17695676 | 0.74 | GSK3B (0.66) | GSK3AGSK3BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016061344-A1 | GSK3 INHIBITORS AND THEIR USES | MIRX PHARMACEUTICALS LLC (US) | 2016-04-21 | — | — | WO | disclosed |