Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PIEZO1 | Q92508 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695691 | 0.93 | GSK3A (0.71) | GSK3AGSK3BTERTALDH1A1NPC1 | |
| SCHEMBL17695697 | 0.91 | GSK3A (0.62) | GSK3AGSK3BTERTALDH1A1NPC1 | |
| SCHEMBL17695693 | 0.89 | GSK3A (0.69) | GSK3AGSK3BTERTALDH1A1NPC1 | |
| SCHEMBL17695702 | 0.89 | GSK3A (0.71) | GSK3AGSK3BALDH1A1NPC1RAB9A | |
| SCHEMBL17695699 | 0.88 | TERT (0.58) | GSK3AGSK3BTERTALDH1A1PIEZO1 | |
| SCHEMBL17695690 | 0.86 | GSK3B (0.81) | GSK3AGSK3BALDH1A1NPC1RAB9A | |
| SCHEMBL17695671 | 0.86 | TERT (0.56) | GSK3AGSK3BTERTALDH1A1PIEZO1 | |
| SCHEMBL17695681 | 0.85 | GSK3A (0.79) | GSK3AGSK3BALDH1A1NPC1RAB9A | |
| SCHEMBL17695686 | 0.84 | GSK3A (0.81) | GSK3AGSK3BALDH1A1NPC1RAB9A | |
| SCHEMBL17695687 | 0.83 | GSK3B (0.69) | GSK3AGSK3BTERTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016061344-A1 | GSK3 INHIBITORS AND THEIR USES | MIRX PHARMACEUTICALS LLC (US) | 2016-04-21 | — | — | WO | disclosed |