Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.42 |
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769615 | 1.00 | PMP22 (0.46) | PMP22DDAH1GCLCSLC1A1GSR | |
| SCHEMBL13585613 | 0.85 | DDAH1 (0.37) | PMP22DDAH1GCLCSLC1A1NOS2 | |
| SCHEMBL13585610 | 0.85 | DDAH1 (0.37) | PMP22DDAH1GCLCSLC1A1NOS2 | |
| SCHEMBL1769669 | 0.84 | DDAH1 (0.42) | PMP22DDAH1GCLCSLC1A1GSR | |
| SCHEMBL1769672 | 0.84 | DDAH1 (0.42) | PMP22DDAH1GCLCSLC1A1GSR | |
| SCHEMBL1769380 | 0.80 | PMP22 (0.47) | PMP22GCLCSLC1A1GSRGRM8 | |
| SCHEMBL1769377 | 0.80 | PMP22 (0.47) | PMP22GCLCSLC1A1GSRGRM8 | |
| SCHEMBL1769843 | 0.80 | PMP22 (0.47) | PMP22GCLCSLC1A1GSRGRM8 | |
| SCHEMBL1769845 | 0.80 | PMP22 (0.47) | PMP22GCLCSLC1A1GSRGRM8 | |
| SCHEMBL6672420 | 0.78 | PMP22 (0.46) | PMP22DDAH1GCLCSLC1A1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754038-B2 | Template-fixed peptidomimetics with CCR10 antagonistic activity | POLYPHOR AG (CH) | 2014-06-17 | — | — | US | disclosed |
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2012-11-08 | — | — | US | disclosed |
| WO-2011060832-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283168-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | CCR10, CCR1, CCRL2 | PMP22 1622/4885DDAH1 3491/4885GCLC 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.