Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.57 |
| ▸ | MEN1 | O00255 | 13/20 | 0.57 |
| ▸ | NPC1 | O15118 | 11/20 | 0.57 |
| ▸ | GAA | P10253 | 11/20 | 0.57 |
| ▸ | RAB9A | P51151 | 11/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.57 |
| ▸ | RELA | Q04206 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873374 | 0.86 | MAPT (0.61) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL17696370 | 0.77 | MAPT (0.57) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL17696368 | 0.75 | NPC1 (0.59) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL22103769 | 0.74 | MAPT (0.64) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL17933603 | 0.74 | MAPT (0.52) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL11020602 | 0.73 | MAPT (0.79) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL1132582 | 0.72 | MAPT (0.58) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL1132583 | 0.72 | MAPT (0.58) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL20628342 | 0.72 | MAPT (0.49) | MAPTKMT2AMEN1NPC1GAA | |
| SCHEMBL1231354 | 0.72 | MAPT (0.70) | MAPTKMT2AMEN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108315-A1 | OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND | FUJIFILM CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |