SCHEMBL1231354

SCHEMBL1231354

C(=NNc1nc2ccccc2s1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 16/20 0.70
▸ RAB9A P51151 13/20 0.70
▸ NPC1 O15118 13/20 0.70
▸ KMT2A Q03164 12/20 0.70
▸ MEN1 O00255 11/20 0.70
▸ GAA P10253 10/20 0.70
▸ SMN1; SMN2 Q16637 10/20 0.70
▸ KDM4E B2RXH2 5/20 0.70
▸ NFKB1 P19838 4/20 0.66
▸ NFKB2 Q00653 4/20 0.66
▸ RELA Q04206 4/20 0.66
▸ TDP1 Q9NUW8 3/20 0.66
▸ NPSR1 Q6W5P4 2/20 0.66
▸ POLB P06746 1/20 0.66
▸ PAX8 Q06710 1/20 0.66
▸ LMNA P02545 5/20 0.65
▸ MAPK1 P28482 3/20 0.65
▸ TP53 P04637 2/20 0.63
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ HPGD P15428 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231353 1.00 MAPT (0.70) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL10038665 0.90 MAPT (0.65) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL1165591 0.88 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL1165592 0.88 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL28684828 0.88 MAPT (0.61) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL21010612 0.85 MAPT (0.68) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL13779288 0.82 MAPT (0.75) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL22103769 0.81 MAPT (0.64) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL27701871 0.81 MAPT (0.62) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL17123531 0.81 MAPT (0.67) MAPTRAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8617897-B2 Method of detecting oxides of nitrogen 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-31 — — US claimed
EP-2462441-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M Innovative Properties Company (US) 2012-06-13 — — EP claimed
US-20120129266-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY 2012-05-24 — — US claimed
WO-2011017317-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-10 — — WO claimed
EP-3789472-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2025-04-16 — — EP disclosed
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen TERUMO KABUSHIKI KAISHA (JP) 2023-11-14 — — US disclosed
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen TERUMO KABUSHIKI KAISHA (JP) 2023-11-14 — — US disclosed
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt TERUMO KABUSHIKI KAISHA (JP) 2023-08-29 — — US disclosed
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt TERUMO KABUSHIKI KAISHA (JP) 2023-08-29 — — US disclosed
US-11674082-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2023-06-13 — — US disclosed
US-11365354-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2022-06-21 — — US disclosed
EP-3789471-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2021-06-09 — — EP disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 — — US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 — — US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 — — US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 — — US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 — — US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 — — US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11815448-B2 Method, reagent, and chip for measuring analyte concentration in specimen STUB1, MPO, ALDH1A2 MAPT 3928/4885RAB9A 4406/4885NPC1 4507/4885
US-11739083-B2 Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt STUB1, BTK, TST MAPT 1351/4885RAB9A 4856/4885NPC1 4612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback