SCHEMBL3597080

SCHEMBL3597080

CC(=O)Oc1c(C)cc(O)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
HTT P42858 4/20 1.00
KDM4E B2RXH2 3/20 1.00
GAA P10253 3/20 1.00
HSD17B10 Q99714 2/20 1.00
TP53 P04637 1/20 1.00
LMNA P02545 2/20 0.52
POLB P06746 3/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NSD2 O96028 1/20 0.46
MCL1 Q07820 1/20 0.46
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.43
BACE1 P56817 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ABCB11 O95342 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetomenaphthone SCHEMBL29411342 0.83 HTT (1.00) MAPTHTTKDM4EGAAHSD17B10
Acetomenaphthone SCHEMBL209382 0.83 HTT (1.00) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL30166016 0.82 MAPT (0.69) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL17696404 0.82 MAPT (0.69) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL3989240 0.82 MAPT (0.69) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL20398637 0.80 HTT (0.67) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL30434021 0.80 HTT (0.67) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL9628320 0.80 MAPT (0.67) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL6907648 0.79 KDM4E (0.63) MAPTHTTKDM4EGAAHSD17B10
SCHEMBL29368738 0.79 KDM4E (0.63) MAPTHTTKDM4EGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778114-B Efficient and environment-friendly method for synthesizing vitamin K1 杭州浙中医药科技有限公司 2025-05-30 CN claimed
CN-112778114-A Efficient and environment-friendly method for synthesizing vitamin K1 杭州浙中医药科技有限公司 2021-05-11 CN claimed
CN-111380966-A Method for determining related substances of vitamin K1 bulk drug 南京艾德凯腾生物医药有限责任公司 2020-07-07 CN claimed
JP-56104805-A None JP disclosed
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT EPIZON PHARMA INC (US) 2026-03-26 US disclosed
US-12514871-B2 Pegylated menaquinol compositions and methods of treatment Epizon Pharma, Inc. (US) 2026-01-06 US disclosed
CN-112778114-B Efficient and environment-friendly method for synthesizing vitamin K1 杭州浙中医药科技有限公司 2025-05-30 CN disclosed
CN-112778114-B Efficient and environment-friendly method for synthesizing vitamin K1 杭州浙中医药科技有限公司 2025-05-30 CN disclosed
CN-119630636-A Pegylated alpha naphthol compositions and methods of treatment 埃皮松制药公司 2025-03-14 CN disclosed
US-12103914-B2 Compositions of biologically active menaquinol derivatives and methods of treatment Epizon Pharma, Inc. (US) 2024-10-01 US disclosed
WO-2023235259-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT Epizon Pharma, Inc. (US) 2023-12-07 WO disclosed
US-20070060761-A1 Method for producing quinone compound EISAI CO., LTD. 2007-03-15 US disclosed
US-20070060761-A1 Method for producing quinone compound EISAI CO., LTD. 2007-03-15 US disclosed
CN-1816536-A Cannabinoid receptor modulators TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2006-08-09 CN disclosed
EP-1637527-A1 CANNABINOID RECEPTOR MODULATOR Takeda Pharmaceutical Company Limited (JP) 2006-03-22 EP disclosed
EP-0592962-B1 Purification method of crude product EISAI KAGAKU KK (JP) 1997-07-16 EP disclosed
US-5547580-A CHROMATOGRAPHY ON A SILICA GEL SOLID SUPPORT USING METHANOL, HEXANE MIXTURE EISAI CHEMICAL CO., LTD. (JP) 1996-08-20 US disclosed
EP-0592962-A1 Purification method of crude product EISAI CHEMICAL CO., LTD. (JP) 1994-04-20 EP disclosed
JP-S56104805-A NOVEL PROCESS FOR NEUTRALIZING TOXICITY OF HERBICIDE AGAINST FISH ASAHI CHEM IND CO LTD 1981-08-20 JP disclosed
US-3957836-A QUINONE DERIVATIVES TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12103914-B2 Compositions of biologically active menaquinol derivatives and methods of treatment GLS, COQ8A, GLS2 MAPT 3057/4885HTT 3046/4885KDM4E 4107/4885
US-20070060761-A1 Method for producing quinone compound SDHA, SQOR, SDHB MAPT 1598/4885HTT 2229/4885KDM4E 1682/4885
US-20260083773-A1 PEGYLATED MENAQUINOL COMPOSITIONS AND METHODS OF TREATMENT SGMS1, SGMS2, MEN1 MAPT 4296/4885HTT 3516/4885KDM4E 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.