Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598394 | 0.97 | — | — | |
| Bromide SCHEMBL1769727 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTTP53 | |
| Hydrochloric Acid SCHEMBL2497190 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTTP53 | |
| SCHEMBL2099455 | 0.94 | KDM4E (0.56) | KDM4ELMNAKMT2AHTTAPOBEC3A | |
| Fluoride Ion SCHEMBL907407 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTCHRNA7 | |
| Hydrochloric Acid SCHEMBL907479 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTTP53 | |
| Water SCHEMBL1769874 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTTP53 | |
| SCHEMBL28908248 | 0.94 | KDM4E (0.50) | KDM4ELMNAKMT2AHTTTP53 | |
| Bromide SCHEMBL9228369 | 0.92 | KDM4E (0.54) | KDM4ELMNAKMT2AHTTAPOBEC3A | |
| Hydrochloric Acid SCHEMBL1769902 | 0.92 | KDM4E (0.54) | KDM4ELMNAKMT2AHTTAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172463-B1 | Quaternary ammonium salt, electrolytic solution and electrochemical device | OTSUKA CHEMICAL CO LTD (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-8747690-B2 | Quaternary ammonium salt and composition, and electrochemical device | OTSUKA CHEMICAL CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8366956-B2 | Quaternary ammonium salt and composition, and electrochemical device | OTSUKA CHEMICAL CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20130004860-A1 | QUATERNARY AMMONIUM SALT AND COMPOSITION, AND ELECTROCHEMICAL DEVICE | STELLA CHEMIFA CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20110123873-A1 | Quaternary ammonium salt and composition, and electrochemical device | STELLA CHEMIFA CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-7834197-B2 | Quaternary ammonium salt, electrolyte, and electrochemical device | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-2172463-A1 | Quaternary ammonium salt, electrolytic solution and electrochemical device | Otsuka Chemical Co., Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-20070042271-A1 | Quaternary ammonium salt, electrolyte, and electrochemical device | OTSUKA CHEMICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1642894-A1 | QUATERNARY AMMONIUM SALT, ELECTROLYTE, AND ELECTROCHEMICAL DEVICE | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2006-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123873-A1 | Quaternary ammonium salt and composition, and electrochemical device | DNMT3A, AFF4, AFF2 | KDM4E 291/4885LMNA 4069/4885KMT2A 200/4885 |
| US-20070042271-A1 | Quaternary ammonium salt, electrolyte, and electrochemical device | DNMT3A, NHERF1, SLC9A1 | KDM4E 448/4885LMNA 2823/4885KMT2A 268/4885 |
| US-20130004860-A1 | QUATERNARY AMMONIUM SALT AND COMPOSITION, AND ELECTROCHEMICAL DEVICE | DNMT3A, AFF4, AFF2 | KDM4E 291/4885LMNA 4069/4885KMT2A 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.