Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658137 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL2584365 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL198605 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL198604 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL22407241 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL22129787 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL22407234 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL22129682 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL22129681 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL163908 | 0.97 | TSHR (0.50) | OPRM1TSHRTHRBLMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184967-A | Functional side chain substituted pyrrolopyrrole diketo-base terpolymer and preparation method and application thereof | 北京印刷学院 | 2024-06-14 | — | — | CN | claimed |
| CN-118201905-A | Cationic lipid | 武田药品工业株式会社 | 2024-06-14 | — | — | CN | claimed |
| WO-2023130008-A2 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-07-06 | — | — | WO | claimed |
| US-11685726-B2 | Pharmaceutical compositions of 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid and ester derivatives thereof | SEA PHARMACEUTICALS LLC (US) | 2023-06-27 | — | — | US | claimed |
| US-20230151049-A1 | Compounds Useful in HIV Therapy | VIIV HEALTHCARE COMPANY (US) | 2023-05-18 | — | — | US | claimed |
| US-20230150971-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)-6-FLUORODECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND ESTER DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-05-18 | — | — | US | claimed |
| US-20230144449-A1 | TERMINAL FUNCTIONAL SIDE CHAIN-SUBSTITUTED DIKETOPYRROLOPYRROLE (DPP)-BASED TERPOLYMER AND PREPARATION METHOD AND USE THEREOF | BEIJING INSTITUTE OF GRAPHIC COMMUNICATION (CN) | 2023-05-11 | — | — | US | claimed |
| EP-4175635-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)-6-FLUORODECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND ESTER DERIVATIVES THEREOF | Sea Pharmaceuticals LLC (US) | 2023-05-10 | — | — | EP | claimed |
| CN-114015021-A | Terminal functional side chain substituted pyrrolopyrroledione-based terpolymer and preparation method and application thereof | 北京印刷学院 | 2022-02-08 | — | — | CN | claimed |
| WO-2022006537-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)-6-FLUORODECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND ESTER DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2022-01-06 | — | — | WO | claimed |
| CN-109942798-A | Terminal siloxane base dovetail side chain substituted azole and pyrroledione based polyalcohol and the preparation method and application thereof | 北京印刷学院 | 2019-06-28 | — | — | CN | claimed |
| EP-3202816-B1 | ADHESIVE MATERIALS CONTAINING ALKOXYSILYL WITH IMPROVED TEARING RESISTANCE | EVONIK DEGUSSA GMBH (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-3202816-A1 | ADHESIVE MATERIALS CONTAINING ALKOXYSILYL WITH IMPROVED TEARING RESISTANCE | Evonik Degussa GmbH (DE) | 2017-08-09 | — | — | EP | claimed |
| EP-2086974-B1 | DIIMIDE-BASED SEMICONDUCTOR MATERIALS AND METHODS OF PREPARING AND USING THE SAME | POLYERA CORP (US) | 2013-07-24 | — | — | EP | claimed |
| EP-1000070-A4 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-06-07 | — | — | EP | claimed |
| EP-1000070-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-05-17 | — | — | EP | claimed |
| EP-0984997-A4 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY LTD (AU) | 2000-03-29 | — | — | EP | claimed |
| EP-0984997-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 2000-03-15 | — | — | EP | claimed |
| WO-1999003863-A1 | SILICON-CONTAINING CHAIN EXTENDERS | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1999-01-28 | — | — | WO | claimed |
| WO-1998054242-A1 | SILICON-BASED POLYCARBONATES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1998-12-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685726-B2 | Pharmaceutical compositions of 6-(2-(2H-tetrazol-5-yl)ethyl)-6-fluorodecahydroisoquinoline-3-carboxylic acid and ester derivatives thereof | KCNQ5, KCNQ2, KCNQ3 | OPRM1 575/4885TSHR 4064/4885THRB 2244/4885 |
| US-20230151049-A1 | Compounds Useful in HIV Therapy | CCR5, CD4, NPC1 | OPRM1 868/4885TSHR 4863/4885THRB 4288/4885 |
| US-20230150971-A1 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)-6-FLUORODECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND ESTER DERIVATIVES THEREOF | KCNQ5, KCNQ2, KCNQ3 | OPRM1 575/4885TSHR 4064/4885THRB 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.