Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13475999 | 0.79 | S1PR1 (0.38) | ORAI1ORAI2ORAI3TRPV6NPC1 | |
| SCHEMBL12314712 | 0.78 | TRPV6 (0.57) | ORAI1ORAI2ORAI3TRPV6NPC1 | |
| SCHEMBL3274135 | 0.77 | NPC1 (0.33) | ORAI1ORAI2ORAI3TRPV6NPC1 | |
| SCHEMBL3274666 | 0.76 | ORAI1 (0.38) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL13476000 | 0.72 | ORAI1 (0.41) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL177405 | 0.72 | TTR (0.50) | — | |
| SCHEMBL29427126 | 0.72 | TTR (0.50) | — | |
| SCHEMBL2408066 | 0.72 | TRPV6 (0.56) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL2400583 | 0.69 | ENPP2 (0.38) | ORAI1ORAI2ORAI3TRPV6NPC1 | |
| SCHEMBL2400579 | 0.69 | ENPP2 (0.32) | ORAI1ORAI2ORAI3TRPV6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |