Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171792 | 0.71 | NOTUM (0.47) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28346864 | 0.70 | NOTUM (0.49) | NUDT1NOTUMSCN9APIK3CDPIK3CB | |
| SCHEMBL2789857 | 0.69 | NUDT1 (0.55) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2789106 | 0.69 | PIK3CA (0.46) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL3232667 | 0.68 | NOTUM (0.51) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL3764747 | 0.67 | NOTUM (0.43) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL5748240 | 0.67 | CRHBP (0.50) | NUDT1NOTUMPIK3CDPIK3CBPIK3CG | |
| SCHEMBL22465938 | 0.66 | NOTUM (0.45) | NUDT1NOTUMSCN9APIK3CDPIK3CB | |
| SCHEMBL29598502 | 0.66 | NOTUM (0.56) | NOTUMPDK1KMT2ARAB9APOLB | |
| SCHEMBL519320 | 0.66 | NOTUM (0.56) | NOTUMPDK1KMT2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010918-A2 | NOVEL SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | Zenith Epigenetics Corp. (CA) | 2016-04-27 | — | — | EP | claimed |