SCHEMBL1769916

SCHEMBL1769916

CC1(C)C(=O)N(C(=O)O)C(=O)N1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628025 0.64 ALDH1A1 (0.35) KMT2A
SCHEMBL11362806 0.61 MAPK1 (0.35)
SCHEMBL25255933 0.56 ALDH1A1 (0.44)
Hydrochloric Acid SCHEMBL9786969 0.54 BLM (0.31)
SCHEMBL11884214 0.53 MEN1 (0.33) KMT2A
SCHEMBL23733143 0.51 LMNA (0.34) KMT2A
Acetic Acid SCHEMBL96751 0.44
Acetic Acid SCHEMBL30765430 0.44
Acetic Acid SCHEMBL7007795 0.44 FFAR3 (0.88)
Acetic Acid SCHEMBL7947408 0.44 FFAR3 (0.88)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026340-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK LLC (US) 2024-01-25 US claimed
EP-3789499-B1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK INC (US) 2023-03-15 EP claimed
EP-3946054-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF Seer, Inc. (US) 2022-02-09 EP claimed
US-20210310071-A1 URINARY MICROBIOMIC PROFILING Convergent Genomics, Inc. 2021-10-07 US claimed
US-20210215709-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF SEER, INC. 2021-07-15 US claimed
EP-2814981-B2 BLOOD COLLECTION METHOD FOR STABILIZING CELL-FREE PLASMA DNA STRECK INC (US) 2021-04-28 EP claimed
EP-3789499-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION Streck, Inc. (US) 2021-03-10 EP claimed
WO-2020198209-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF SEER, INC. (US) 2020-10-01 WO claimed
EP-3225699-B1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK INC (US) 2020-09-30 EP claimed
US-20200255819-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2020-08-13 US claimed
EP-2888354-B1 VIRUS PARTICLE STABILISATION AND METHOD FOR ISOLATING VIRAL NUCLEIC ACIDS QIAGEN GMBH (DE) 2020-04-01 EP claimed
EP-2888363-B1 METHOD FOR ISOLATING NUCLEIC ACIDS FROM A FORMALDEHYDE RELEASER STABILIZED SAMPLE QIAGEN GMBH (DE) 2018-06-06 EP claimed
EP-2814981-B1 BLOOD COLLECTION DEVICE FOR STABILIZING CELL-FREE PLASMA DNA STRECK INC (US) 2017-06-28 EP claimed
US-20140080112-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK, INC. 2014-03-20 US claimed
US-20100209930-A1 PRESERVATION OF CELL-FREE NUCLEIC ACIDS STRECK, INC. (US) 2010-08-19 US claimed
US-20100184069-A1 PRESERVATION OF FETAL NUCLEIC ACIDS IN MATERNAL PLASMA STRECK, INC. (US) 2010-07-22 US claimed
US-20100167271-A1 METHOD FOR SCREENING BLOOD USING A PRESERVATIVE THAT MAY BE IN A SUBSTANTIALLY SOLID STATE FORM STRECK, INC. (US) 2010-07-01 US claimed
EP-1816461-A1 Method and device for collecting and preserving cells for analysis Streck Laboratories, Inc. (US) 2007-08-08 EP claimed
EP-1413874-A1 Method and device for collecting and preserving cells for analysis Streck Laboratories, Inc. (US) 2004-04-28 EP claimed
US-20240026340-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK LLC (US) 2024-01-25 US disclosed
WO-2023228174-A9 USEFUL COMBINATIONS OF RESTRICTION ENZYMES NUCLEIX LTD. (IL) 2023-12-28 WO disclosed
WO-2023227954-A1 SAMPLE PREPARATION FOR CELL-FREE DNA ANALYSIS NUCLEIX LTD. (IL) 2023-11-30 WO disclosed
US-11746372-B2 Rapid nucleic acids separation and sample preparation via hollow-centered silica microsphere GODX, INC. (US) 2023-09-05 US disclosed
WO-2023154967-A2 DIAGNOSIS OF COLORECTAL CANCER USING TARGETED QUANTIFICATION OF SITE-SPECIFIC PROTEIN GLYCOSYLATION VENN BIOSCIENCES CORPORATION (US) 2023-08-17 WO disclosed
WO-2023135487-A2 METHOD FOR ANALYZING BLOOD STORED FOR LATER ANALYSIS OF CELL FREE DNA LITTLE STEPHEN (GB) 2023-07-20 WO disclosed
US-20230180742-A1 Compositions and Methods for Stabilizing Circulating Tumor Cells STRECK LLC 2023-06-15 US disclosed
US-20230160881-A1 HMGB1 RNA And Methods Therefor NANTOMICS LLC (US) 2023-05-25 US disclosed
WO-2023089613-A1 WHOLE GENOME CPG ANALYSIS NUCLEIX LTD. (IL) 2023-05-25 WO disclosed
US-11647743-B2 Method and device for collecting and preserving cells for analysis STRECK LLC (US) 2023-05-16 US disclosed
US-11634747-B2 Preservation of fetal nucleic acids in maternal plasma STRECK LLC (US) 2023-04-25 US disclosed
EP-3789499-B1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK INC (US) 2023-03-15 EP disclosed
US-20230076807-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS AND USES THEREOF SEER, INC. 2023-03-09 US disclosed
EP-4136972-A1 COMPOSITIONS AND METHODS FOR STABILIZING CIRCULATING TUMOR CELLS Streck, Inc. (US) 2023-02-22 EP disclosed
US-11547111-B2 Compositions and methods for stabilizing circulating tumor cells STRECK, INC. (US) 2023-01-10 US disclosed
EP-3946054-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF Seer, Inc. (US) 2022-02-09 EP disclosed
US-20210215709-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF SEER, INC. 2021-07-15 US disclosed
US-20210180108-A1 RAPID NUCLEIC ACIDS SEPARATION AND SAMPLE PREPARATION VIA HOLLOW-CENTERED SILICA MICROSPHERE GODX, INC (US) 2021-06-17 US disclosed
EP-2814981-B2 BLOOD COLLECTION METHOD FOR STABILIZING CELL-FREE PLASMA DNA STRECK INC (US) 2021-04-28 EP disclosed
US-10966421-B2 Method and device for collecting and preserving cells for analysis STRECK, INC. (US) 2021-04-06 US disclosed
EP-3789499-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION Streck, Inc. (US) 2021-03-10 EP disclosed
US-20200377955-A1 USE OF CELL-FREE CIRCULATING RNA (cfRNA) EXPRESSION OF PD-L1 AND ERCC1 IN PLASMA TO MONITOR RESPONSE TO THERAPY IN NSCLC NANTHEALTH LABS, INC. 2020-12-03 US disclosed
US-20200315163-A1 Compositions and Methods for Stabilizing Circulating Tumor Cells JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2020-10-08 US disclosed
WO-2020198209-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF SEER, INC. (US) 2020-10-01 WO disclosed
EP-3225699-B1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK INC (US) 2020-09-30 EP disclosed
US-20200255819-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2020-08-13 US disclosed
US-20200248267-A1 TUMOR VS. MATCHED NORMAL cfRNA NANTOMICS LLC (US) 2020-08-06 US disclosed
US-10674721-B2 Compositions and methods for stabilizing circulating tumor cells STRECK, INC. (US) 2020-06-09 US disclosed
US-20200165685-A1 CIRCULATING RNA FOR DETECTION, PREDICTION, AND MONITORING OF CANCER NANTOMICS, LLC 2020-05-28 US disclosed
EP-3642351-A1 USE OF CELL-FREE CIRCULATING RNA (cfRNA) EXPRESSION OF PD-L1 AND ERCC1 IN PLASMA TO MONITOR RESPONSE TO THERAPY IN NSCLC Nantomics, LLC (US) 2020-04-29 EP disclosed
EP-3628057-A2 TUMOR VS. MATCHED NORMAL cfRNA Nantomics, LLC (US) 2020-04-01 EP disclosed
EP-3622071-A1 CIRCULATING RNA FOR DETECTION, PREDICTION, AND MONITORING OF CANCER Nantomics, LLC (US) 2020-03-18 EP disclosed
US-20190300948-A1 METHODS FOR IDENTIFICATION OF SAMPLES DNAME-IT NV (BE) 2019-10-03 US disclosed
WO-2019183263-A1 INSTRUMENTATION-FREE PAPER ORIGAMIRAPID MOLECULAR DIAGNOSTIC DEVICE GODX, INC. (US) 2019-09-26 WO disclosed
EP-3458606-A1 METHODS FOR IDENTIFICATION OF SAMPLES DName-iT NV (BE) 2019-03-27 EP disclosed
WO-2019055851-A1 HMGB1 RNA AND METHODS THEREFOR NANTOMICS, LLC (US) 2019-03-21 WO disclosed
US-20190075785-A1 Compositions and Methods for Stabilizing Circulating Tumor Cells JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-03-14 US disclosed
WO-2018236811-A1 USE OF CELL-FREE CIRCULATING RNA (cfRNA) EXPRESSION OF PD-L1 AND ERCC1 IN PLASMA TO MONITOR RESPONSE TO THERAPY IN NSCLC NANTCELL, INC. (US) 2018-12-27 WO disclosed
WO-2018208892-A1 CIRCULATING RNA FOR DETECTION, PREDICTION, AND MONITORING OF CANCER NANTOMICS, LLC (US) 2018-11-15 WO disclosed
WO-2018204377-A2 TUMOR VS. MATCHED NORMAL cfRNA NANTOMICS, LLC (US) 2018-11-08 WO disclosed
US-10091984-B2 Compositions and methods for stabilizing circulating tumor cells STRECK, INC. (US) 2018-10-09 US disclosed
WO-2018145005-A1 SAMPLE COLLECTION TUBE WITH PRESERVATIVE STRECK, INC. (US) 2018-08-09 WO disclosed
WO-2017198742-A1 METHODS FOR IDENTIFICATION OF SAMPLES DNAME-IT NV (BE) 2017-11-23 WO disclosed
EP-3246412-A1 METHODS FOR IDENTIFICATION OF SAMPLES DName-iT NV (BE) 2017-11-22 EP disclosed
EP-3225699-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION Streck, Inc. (US) 2017-10-04 EP disclosed
EP-2814981-B1 BLOOD COLLECTION DEVICE FOR STABILIZING CELL-FREE PLASMA DNA STRECK INC (US) 2017-06-28 EP disclosed
US-9657227-B2 Preservation of cell-free RNA in blood samples STRECK, INC. (US) 2017-05-23 US disclosed
US-20160174544-A1 Compositions and Methods for Stabilizing Circulating Tumor Cells JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-06-23 US disclosed
US-20160143268-A1 METHOD AND DEVICE FOR COLLECTING AND PRESERVING CELLS FOR ANALYSIS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-05-26 US disclosed
US-20140080112-A1 BLOOD COLLECTION DEVICE FOR IMPROVED NUCLEIC ACID REGULATION STRECK, INC. 2014-03-20 US disclosed
US-20140054508-A1 PRESERVATION OF CELL-FREE RNA IN BLOOD SAMPLES STRECK, INC. (US) 2014-02-27 US disclosed
US-8304187-B2 Preservation of cell-free RNA in blood samples STRECK, INC. (US) 2012-11-06 US disclosed
US-20110300608-A1 NUCLEIC ACID ISOLATION IN PRESERVED WHOLE BLOOD STRECK, INC. (US) 2011-12-08 US disclosed
US-20110111410-A1 STABILIZATION OF RNA IN INTACT CELLS WITHIN A BLOOD SAMPLE STRECK, INC. (US) 2011-05-12 US disclosed
US-20100317107-A1 METHOD AND DEVICE FOR COLLECTING AND PRESERVING CELLS FOR ANALYSIS STRECK, INC. (US) 2010-12-16 US disclosed
US-20100209930-A1 PRESERVATION OF CELL-FREE NUCLEIC ACIDS STRECK, INC. (US) 2010-08-19 US disclosed
US-20100184069-A1 PRESERVATION OF FETAL NUCLEIC ACIDS IN MATERNAL PLASMA STRECK, INC. (US) 2010-07-22 US disclosed
US-20100167271-A1 METHOD FOR SCREENING BLOOD USING A PRESERVATIVE THAT MAY BE IN A SUBSTANTIALLY SOLID STATE FORM STRECK, INC. (US) 2010-07-01 US disclosed
EP-1816461-A1 Method and device for collecting and preserving cells for analysis Streck Laboratories, Inc. (US) 2007-08-08 EP disclosed
US-20040137417-A1 METHOD AND DEVICE FOR COLLECTING AND PRESERVING CELLS FOR ANALYSIS STRECK LABORATORIES INC. (US) 2004-07-15 US disclosed
EP-1413874-A1 Method and device for collecting and preserving cells for analysis Streck Laboratories, Inc. (US) 2004-04-28 EP disclosed
EP-1413874-A1 Method and device for collecting and preserving cells for analysis Streck Laboratories, Inc. (US) 2004-04-28 EP disclosed