Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240105 | 0.86 | SSTR4 (0.37) | CPN1CPB2AURKARPS6KB1TRPV1 | |
| SCHEMBL2240112 | 0.86 | SSTR4 (0.37) | CPN1CPB2AURKARPS6KB1TRPV1 | |
| SCHEMBL177002 | 0.76 | CPN1 (0.38) | CPN1CPB2AURKARPS6KB1L3MBTL1 | |
| SCHEMBL12348090 | 0.70 | SSTR4 (0.34) | — | |
| SCHEMBL176708 | 0.67 | GRM2 (0.41) | SMN1; SMN2 | |
| SCHEMBL12090415 | 0.67 | ALDH1A1 (0.51) | — | |
| SCHEMBL4732524 | 0.66 | AOC3 (0.47) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL4732525 | 0.66 | AOC3 (0.47) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL16824912 | 0.64 | CPN1 (0.43) | CPN1CPB2L3MBTL1SMN1; SMN2ADRB2 | |
| M-Xylene SCHEMBL28770631 | 0.63 | HPGD (0.46) | TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |