Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240108 | 0.86 | BACE1 (0.43) | CPN1CPB2AOC3L3MBTL1KDM4E | |
| SCHEMBL177001 | 0.76 | CPN1 (0.37) | CPN1CPB2L3MBTL1AURKARPS6KB1 | |
| SCHEMBL16824912 | 0.74 | CPN1 (0.43) | CPN1CPB2AOC3L3MBTL1KDM4E | |
| SCHEMBL21834849 | 0.67 | MEN1 (0.61) | KDM4EMEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL6493022 | 0.67 | AOC3 (0.51) | CPN1CPB2AOC3L3MBTL1MEN1 | |
| SCHEMBL4460226 | 0.67 | ADRB3 (0.45) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4460219 | 0.67 | ADRB3 (0.45) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7116379 | 0.65 | KDM4E (0.47) | AOC3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7116373 | 0.65 | KDM4E (0.47) | AOC3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5466349 | 0.65 | LMNA (0.59) | CPN1CPB2AOC3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |