⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948655 | 0.81 | — | — | |
| SCHEMBL17705131 | 0.77 | CYP2D6 (0.55) | — | |
| SCHEMBL16123439 | 0.77 | MCL1 (0.47) | — | |
| SCHEMBL23489532 | 0.76 | MEN1 (0.54) | — | |
| SCHEMBL17701600 | 0.76 | HPGD (0.41) | — | |
| SCHEMBL15948601 | 0.74 | CASP2 (0.48) | — | |
| SCHEMBL20243588 | 0.74 | MEN1 (0.37) | — | |
| SCHEMBL14559794 | 0.73 | — | — | |
| SCHEMBL16629055 | 0.73 | — | — | |
| SCHEMBL17245246 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170252410-A1 | INSULIN VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2017-09-07 | — | — | US | disclosed |
| US-20170216449-A1 | THERAPEUTIC VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2017-08-03 | — | — | US | disclosed |
| US-9616109-B2 | Insulin vitamin D conjugates | EXTEND BIOSCIENCES, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-9585934-B2 | Therapeutic vitamin D conjugates | EXTEND BIOSCIENCES, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160113993-A1 | THERAPEUTIC VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2016-04-28 | — | — | US | disclosed |
| US-20160114049-A1 | RNAi VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2016-04-28 | — | — | US | disclosed |
| US-20160114001-A1 | INSULIN VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2016-04-28 | — | — | US | disclosed |