Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FABP4 | P15090 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25935846 | 0.77 | CYP2D6 (0.55) | CYP2D6HIF1AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL17701596 | 0.77 | — | — | |
| SCHEMBL17701600 | 0.76 | HPGD (0.41) | ALDH1A1USP2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL24795949 | 0.74 | CYP2D6 (0.50) | CYP2D6HIF1AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL144220 | 0.74 | — | — | |
| SCHEMBL2034998 | 0.74 | CYP2D6 (1.00) | CYP2D6HIF1AGAAALDH1A1FABP4 | |
| SCHEMBL21389247 | 0.72 | TSHR (0.48) | CYP2D6HIF1AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL26747622 | 0.71 | CYP2D6 (0.60) | CYP2D6HIF1AGAAL3MBTL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28227410 | 0.71 | CYP2D6 (0.92) | CYP2D6HIF1AGAAALDH1A1FABP4 | |
| SCHEMBL17701602 | 0.70 | CYP2C19 (0.39) | CYP2D6HIF1AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114049-A1 | RNAi VITAMIN D CONJUGATES | EXTEND BIOSCIENCES, INC. (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114049-A1 | RNAi VITAMIN D CONJUGATES | VDR, CYP2R1, CYP24A1 | CYP2D6 1693/4885HIF1A 2469/4885GAA 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.