Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15781702 | 0.93 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL15782701 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL15782883 | 0.92 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL15782707 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2AGLAKDM5A | |
| SCHEMBL17705606 | 0.88 | KMT2A (0.43) | SMN1; SMN2MEN1KMT2ATSHRKDM5A | |
| SCHEMBL15781707 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL15782700 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL15782977 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ATSHRGLA | |
| SCHEMBL8747997 | 0.84 | KMT2A (0.56) | MEN1KMT2ATSHRKDM5AKDM4E | |
| SCHEMBL14161520 | 0.84 | KMT2A (0.56) | MEN1KMT2ATSHRKDM5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439968-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | SMN1; SMN2 3092/4885MEN1 2774/4885KMT2A 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.