Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273020 | 0.77 | — | — | |
| SCHEMBL29178251 | 0.77 | TDP1 (0.38) | TDP1CYP1A2ALDH1A1POLB | |
| SCHEMBL9468746 | 0.76 | — | — | |
| SCHEMBL2067520 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3831383 | 0.74 | TDP1 (0.36) | TDP1CYP1A2ALDH1A1POLB | |
| Bromide SCHEMBL16765046 | 0.74 | TDP1 (0.36) | TDP1CYP1A2ALDH1A1POLB | |
| SCHEMBL1164351 | 0.74 | ALDH1A1 (0.32) | TDP1CYP1A2ALDH1A1 | |
| SCHEMBL6899919 | 0.73 | CA1 (0.36) | ALDH1A1POLB | |
| SCHEMBL4280147 | 0.73 | — | — | |
| SCHEMBL3469116 | 0.72 | MC4R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110063951-A | Improve the Compounds and methods for of impaired endogenous fibrinolysis using histone deacetylase mortifier | 赛伦诺科学有限公司 | 2019-07-30 | — | — | CN | disclosed |
| US-8378092-B2 | Chlorothiophene-amides as inhibitors of coagulation factors Xa and thrombin | SANOFI (FR) | 2013-02-19 | — | — | US | disclosed |
| US-20110112075-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112075-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | F12, F3, F2 | TDP1 407/4885CYP1A2 376/4885ALDH1A1 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.