⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178251 | 1.00 | TDP1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3831383 | 0.97 | TDP1 (0.36) | — | |
| Bromide SCHEMBL16765046 | 0.97 | TDP1 (0.36) | — | |
| Formic Acid SCHEMBL29763161 | 0.92 | CYP1A2 (0.39) | — | |
| SCHEMBL295238 | 0.92 | HSD17B10 (0.38) | — | |
| SCHEMBL141255 | 0.83 | HSD17B10 (0.44) | — | |
| SCHEMBL180596 | 0.83 | — | — | |
| SCHEMBL9533256 | 0.82 | — | — | |
| Cadaverine Tartrate SCHEMBL4254057 | 0.80 | TSHR (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL28965161 | 0.80 | CHRM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3082 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042772-A1 | FURO PYRIMIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2026-02-12 | — | — | US | claimed |
| US-12516059-B2 | Pyrazolopyridine compounds and uses thereof | INCYTE CORPORATION (US) | 2026-01-06 | — | — | US | claimed |
| US-20250206730-A1 | THIAZOLE DERIVATIVE COMPOUND AND USES THEREOF | AUTOTELIC BIO INC. (KR) | 2025-06-26 | — | — | US | claimed |
| CN-116648250-B | Novel quinazoline derivatives as SOS1 inhibitors and uses thereof | 韩美药品株式会社 | 2025-06-13 | — | — | CN | claimed |
| EP-4501928-A1 | THIAZOLE DERIVATIVE COMPOUND AND USES THEREOF | Autotelic Bio Inc. (KR) | 2025-02-05 | — | — | EP | claimed |
| CN-119371356-A | Nuciferine derivative, and preparation method and application thereof | 云南中医药大学 | 2025-01-28 | — | — | CN | claimed |
| CN-119255993-A | Thiazole derivative compound and use thereof | 奥托泰利克生物公司 | 2025-01-03 | — | — | CN | claimed |
| CN-114746414-B | Aza-quinoline compounds and uses thereof | 诺华公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | claimed |
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | claimed |
| WO-1991019733-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-12-26 | — | — | WO | claimed |
| EP-0412820-A2 | 2-Oxo-1-oxa-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-13 | — | — | EP | claimed |
| US-4716162-A | BRAIN FUNCTION | SANKYO COMPANY, LIMITED (JP) | 1987-12-29 | — | — | US | claimed |
| EP-0111455-A2 | Unsaturated lactones | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | claimed |
| US-4393210-A | ANALGESIC, ANTIULCER, ANTIDEPRESSANT, ANTIHISTAMINE, ANTICHOLINERGIC | SEIYAKU CO., LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| US-4020059-A | Process for preparing tertiary amines | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) | 1977-04-26 | — | — | US | claimed |
| US-3960858-A | 3-Hetero acyl-2,3-benzoxazepines | GRUPPO LEPETIT S.P.A. (IT) | 1976-06-01 | — | — | US | claimed |
| US-3937715-A | PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | claimed |