Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HPGD | P15428 | 9/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15881215 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4857839 | 0.70 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14559557 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19472829 | 0.70 | MAPT (0.69) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL620680 | 0.69 | KDM4E (0.67) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19472596 | 0.68 | MAPT (0.83) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13866406 | 0.67 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL195375 | 0.67 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17444777 | 0.67 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19478571 | 0.67 | HPGD (0.70) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716285-B9 | Compounds for treating and/or preventing diseases associated with bone loss | CENTRE NAT DE LA RECH SCIENT -CNRS- (FR) | 2017-03-01 | — | — | EP | disclosed |
| EP-2716285-B1 | Compounds for treating and/or preventing diseases associated with bone loss | CENTRE NAT RECH SCIENT (FR) | 2016-04-27 | — | — | EP | disclosed |