Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139400 | 0.97 | PRMT6 (0.47) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL13208053 | 0.97 | PRMT6 (0.47) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL26128147 | 0.91 | ADORA3 (0.48) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL26128153 | 0.91 | ADORA3 (0.48) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL18288612 | 0.90 | PRMT6 (0.47) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL26126228 | 0.90 | PRMT6 (0.43) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL26126224 | 0.90 | PRMT6 (0.43) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL13208050 | 0.86 | ADORA3 (0.48) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL16206177 | 0.81 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2P2RY12 | |
| SCHEMBL13020687 | 0.81 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355805-A1 | Double Stranded Oligonucleotide Compounds Comprising Positional Modifications | QUARK PHARMACEUTICALS, INC. | 2016-12-08 | — | — | US | disclosed |
| EP-2649181-B1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOUNDS COMPRISING POSITIONAL MODIFICATIONS | QUARK PHARMACEUTICALS INC (US) | 2016-04-27 | — | — | EP | disclosed |