Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442590 | 0.95 | PIK3CD (0.36) | GRIN2BGRIN2CPIK3CDABL1EGFR | |
| SCHEMBL444534 | 0.81 | SLC6A3 (0.37) | GRIN2BGRIN2C | |
| SCHEMBL442630 | 0.80 | GPR119 (0.33) | GRIN2BGRIN2CCNR2 | |
| SCHEMBL1692041 | 0.79 | CNR2 (0.34) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL446410 | 0.78 | KCNQ2 (0.39) | — | |
| SCHEMBL444476 | 0.76 | GRIN2B (0.32) | GRIN2BGRIN2CCNR2 | |
| SCHEMBL442485 | 0.76 | GRIN2B (0.32) | GRIN2BGRIN2CCNR2 | |
| SCHEMBL441894 | 0.75 | KCNQ2 (0.36) | GRIN2BGRIN2CCNR2 | |
| SCHEMBL441389 | 0.75 | GRIN2B (0.32) | GRIN2BGRIN2C | |
| SCHEMBL444129 | 0.75 | KCNQ2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684871-B1 | Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives | HOFFMANN LA ROCHE (CH) | 2016-05-04 | — | — | EP | disclosed |