Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709143 | 1.00 | CNR2 (0.43) | CNR2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL28384130 | 1.00 | CNR2 (0.43) | CNR2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL29528192 | 1.00 | CNR2 (0.43) | CNR2KDM4ELMNACYP1A2CCR1 | |
| SCHEMBL28741624 | 0.85 | CNR2 (0.35) | CNR2KDM4ELMNACYP1A2CCR1 | |
| Hydrochloric Acid SCHEMBL7176423 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7176559 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7183257 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7180528 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7183592 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7176684 | 0.83 | CNR2 (0.41) | CNR2KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307432-A | Synthesis method of alpha-substituted amide compound | 南京工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307431-A | Method for synthesizing beta-alkylamide from N-phenyl-3-butenamide | 南京工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307433-A | Synthesis method of beta alkylamide | 南京工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-113372318-A | Preparation method and device of 7-methoxy-4' -methyl formate flavanone | 贵州中医药大学 | 2021-09-10 | — | — | CN | claimed |
| CN-118307431-A | Method for synthesizing beta-alkylamide from N-phenyl-3-butenamide | 南京工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118307431-A | Method for synthesizing beta-alkylamide from N-phenyl-3-butenamide | 南京工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118307432-A | Synthesis method of alpha-substituted amide compound | 南京工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118307433-A | Synthesis method of beta alkylamide | 南京工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-116444400-A | Chiral alpha- (trichloromethyl) amine compound and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-115397824-A | Process for preparing COT inhibitor compounds | 吉利德科学公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-113912617-A | Substituted tricycles and methods of use | 艾伯维公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108349930-B | Substituted tricycles and methods of use | 艾伯维公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20170190693-A1 | SUBSTITUTED CHROMANES AND METHOD OF USE | ABBVIE S À R L (LU) | 2017-07-06 | — | — | US | disclosed |
| US-9642831-B2 | Substituted chromanes and method of use | ABBVIE S.Á.R.L. (LU) | 2017-05-09 | — | — | US | disclosed |
| US-20170015675-A1 | SUBSTITUTED TRICYCLICS AND METHOD OF USE | ABBVIE OVERSEAS S.Á.R.L. (LU) | 2017-01-19 | — | — | US | disclosed |
| WO-2017009804-A1 | SUBSTITUTED TRICYCLICS AND METHOD OF USE | ABBVIE S.Á.R.L. (LU) | 2017-01-19 | — | — | WO | disclosed |
| WO-2016160168-A1 | ALIPHATIC-AROMATIC HETEROCYCLIC COMPOUNDS AND USES THEREOF IN METAL EXTRACTANT COMPOSITIONS | CYTEC INDUSTRIES INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20160244860-A1 | ALIPHATIC-AROMATIC HETEROCYCLIC COMPOUNDS AND USES THEREOF IN METAL EXTRACTANT COMPOSITIONS | CYTEC IND INC (US) | 2016-08-25 | — | — | US | disclosed |
| WO-2016069757-A1 | SUBSTITUTED CHROMANES AND METHOD OF USE | ABBVIE INC. (US) | 2016-05-06 | — | — | WO | disclosed |
| US-20160120841-A1 | SUBSTITUTED CHROMANES AND METHOD OF USE | ABBVIE GLOBAL LIMITED (BM) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015675-A1 | SUBSTITUTED TRICYCLICS AND METHOD OF USE | CFTR, F12, CHRM2 | CNR2 322/4885KDM4E 4714/4885LMNA 3799/4885 |
| US-20170190693-A1 | SUBSTITUTED CHROMANES AND METHOD OF USE | CFTR, CHRM3, CHRM2 | CNR2 567/4885KDM4E 4039/4885LMNA 3737/4885 |
| US-20160120841-A1 | SUBSTITUTED CHROMANES AND METHOD OF USE | CFTR, CHRM3, CHRM2 | CNR2 567/4885KDM4E 4039/4885LMNA 3737/4885 |
| US-20160244860-A1 | ALIPHATIC-AROMATIC HETEROCYCLIC COMPOUNDS AND USES THEREOF IN METAL EXTRACTANT COMPOSITIONS | ATIC, ALK, ME1 | CNR2 2130/4885KDM4E 1539/4885LMNA 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.