Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042020 | 0.77 | ALDH1A1 (0.63) | ALDH1A1TDP1MAPTCYP3A4MEN1 | |
| SCHEMBL8167265 | 0.76 | NR4A1 (0.61) | ALDH1A1TDP1CASP1MAPTCYP3A4 | |
| SCHEMBL11039400 | 0.76 | NR4A1 (0.35) | ALDH1A1MAPTNR4A1MEN1KMT2A | |
| SCHEMBL11039151 | 0.76 | TSHR (0.45) | ALDH1A1MAPTCYP3A4TSHRNR4A1 | |
| SCHEMBL11042061 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPTCYP3A4TSHR | |
| SCHEMBL29087015 | 0.74 | NR4A1 (0.48) | ALDH1A1TDP1MAPTCYP3A4TSHR | |
| SCHEMBL55593 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1CASP1MAPTCYP3A4 | |
| SCHEMBL29569367 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1CASP1MAPTCYP3A4 | |
| SCHEMBL29221829 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TDP1MAPTCYP3A4TSHR | |
| SCHEMBL31713018 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TDP1CASP1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | claimed |
| US-20110251418-A1 | CASR AGONISTS | AJINOMOTO CO., INC. (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-4472308-A | Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group | ICI UNITED STATES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4225491-A | REACTIVE DYES FOR COTTON | ICI UNITED STATES, INC. (US) | 1980-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251418-A1 | CASR AGONISTS | CASR, GIPR, GRIK5 | ALDH1A1 2705/4885TDP1 3524/4885CASP1 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.