SCHEMBL17713610

SCHEMBL17713610

CCOc1ccc(-c2sc(-c3ccc(N(c4ccc(-c5sc(-c6ccc(OCC)cc6)c6c5OCCO6)cc4)c4ccc(-c5sc(-c6ccc(OCC)cc6)c6c5OCCO6)cc4)cc3)c3c2OCCO3)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.40
KDM4E B2RXH2 9/20 0.38
SMN1; SMN2 Q16637 7/20 0.38
RAB9A P51151 7/20 0.38
NPC1 O15118 6/20 0.38
HSD17B10 Q99714 3/20 0.38
TP53 P04637 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 6/20 0.36
HPGD P15428 3/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17725550 0.94 ALDH1A1 (0.39) KDM4ESMN1; SMN2RAB9ANPC1HSD17B10
SCHEMBL17713611 0.89 CYP2D6 (0.41) KDM4ESMN1; SMN2RAB9ANPC1HSD17B10
SCHEMBL17713607 0.85 NR5A1 (0.42) KDM4ERAB9ATP53ALDH1A1HPGD
SCHEMBL17713612 0.85 APP (0.43) KDM4ENPC1HSD17B10KMT2AALDH1A1
SCHEMBL18296615 0.85 APP (0.43) KDM4ENPC1HSD17B10KMT2AALDH1A1
SCHEMBL18294661 0.81 ALOX5 (0.45) KDM4ESMN1; SMN2RAB9ANPC1HSD17B10
SCHEMBL15591173 0.80 NISCH (0.39) KDM4ESMN1; SMN2RAB9ANPC1ALDH1A1
SCHEMBL19700322 0.79 FYN (0.36) KDM4ERAB9ANPC1MEN1KMT2A
SCHEMBL15591185 0.77 APP (0.35) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL15441171 0.77 APP (0.38) KDM4ENPC1HSD17B10KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016066494-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2016-05-06 WO disclosed
WO-2016066494-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2016-05-06 WO disclosed