Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725672 | 1.00 | ADRB2 (0.56) | ADRB2KDM1ADRD2DRD4TBXA2R | |
| SCHEMBL17713982 | 0.91 | KDM1A (0.55) | ADRB2KDM1ADRD2DRD4TBXA2R | |
| SCHEMBL17713956 | 0.87 | MAPT (0.46) | ADRB2KDM1AGAAFYN | |
| SCHEMBL17725771 | 0.87 | MAPT (0.46) | ADRB2KDM1AGAAFYN | |
| SCHEMBL5319112 | 0.83 | SLC22A1 (0.50) | ADRB2KDM1AMEN1GAAKMT2A | |
| SCHEMBL17725791 | 0.83 | ADRB2 (0.38) | ADRB2KDM1ATBXA2RGAA | |
| SCHEMBL17713979 | 0.83 | ADRB2 (0.38) | ADRB2KDM1ATBXA2RGAA | |
| SCHEMBL17713968 | 0.82 | ADRB2 (0.50) | ADRB2TBXA2RMEN1ABL1ALPL | |
| SCHEMBL17725635 | 0.82 | ADRB2 (0.50) | ADRB2TBXA2RMEN1ABL1ALPL | |
| SCHEMBL17713948 | 0.81 | ADRB2 (0.49) | ADRB2DRD2TBXA2RMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104161758-A | Applications of tetrahydroisoquinoline-3-carboxylic acid derivatives in preparation of medicines treating dopaminergic nerve diseases | UNIV SOOCHOW | 2014-11-26 | — | — | CN | claimed |
| CN-104161758-B | 3 carboxylic acid tetrahydro isoquinoline derivatives are preparing the application in treating dopaminergic nerve disease medicament | 苏州大学 | 2018-01-02 | — | — | CN | disclosed |
| WO-2016065425-A1 | BIOTRANSFORMATION REACTIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-05-06 | — | — | WO | disclosed |
| CN-104161758-A | Applications of tetrahydroisoquinoline-3-carboxylic acid derivatives in preparation of medicines treating dopaminergic nerve diseases | UNIV SOOCHOW | 2014-11-26 | — | — | CN | disclosed |