Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 5/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714002 | 0.87 | AKT1 (0.43) | NR1D1AKT1KDM4EALDH1A1TSHR | |
| SCHEMBL17714029 | 0.86 | AKT1 (0.45) | NR1D1AKT1KDM4EALDH1A1TSHR | |
| SCHEMBL7570965 | 0.86 | AKT1 (0.50) | NR1D1AKT1TSHRNR1H3CTSL | |
| SCHEMBL7562431 | 0.84 | AKT1 (0.49) | NR1D1AKT1TSHRNR1H3CTSL | |
| SCHEMBL17713996 | 0.83 | HCRTR2 (0.42) | HCRTR2KDM4EALDH1A1TSHRACHE | |
| SCHEMBL17714014 | 0.83 | ITGA4 (0.56) | NR1D1ALDH1A1NR1H3CTSB | |
| SCHEMBL23130693 | 0.83 | AKT1 (0.50) | NR1D1AKT1TSHRNR1H3CTSL | |
| SCHEMBL8018235 | 0.83 | AKT1 (0.50) | NR1D1AKT1TSHRNR1H3CTSL | |
| SCHEMBL30915258 | 0.83 | AKT1 (0.50) | NR1D1AKT1TSHRNR1H3CTSL | |
| SCHEMBL25539127 | 0.81 | AKT1 (0.48) | NR1D1AKT1TSHRNR1H3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | KATHOLIEKE UNIVERSITET LEUVEN (BE) | 2022-08-23 | — | — | US | disclosed |
| EP-3212610-B1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | UNIV LEUVEN KATH (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | US | disclosed |
| EP-3212610-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | Katholieke Universiteit Leuven (BE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016065435-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | H1-3, H1-0, H1-2 | NR1D1 3515/4885HCRTR2 4676/4885AKT1 4264/4885 |
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | H1-3, H1-0, H1-2 | NR1D1 3528/4885HCRTR2 4674/4885AKT1 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.