Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 6/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.56 |
| ▸ | NR1D1 | P20393 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17713993 | 0.85 | ALDH1A1 (0.52) | ITGA4ITGB7ALDH1A1LMNACYP1A2 | |
| SCHEMBL17714002 | 0.84 | AKT1 (0.43) | NR1D1ALDH1A1NR1H3CTSBTDP1 | |
| SCHEMBL17714005 | 0.83 | NR1D1 (0.45) | NR1D1ALDH1A1NR1H3CTSB | |
| Trifluoroacetic Acid SCHEMBL17713998 | 0.81 | ALDH1A1 (0.46) | ITGA4ITGB7ALDH1A1LMNACYP1A2 | |
| SCHEMBL17714029 | 0.80 | AKT1 (0.45) | ITGA4ITGB7NR1D1ALDH1A1NR1H3 | |
| SCHEMBL7570965 | 0.80 | AKT1 (0.50) | NR1D1LMNANR1H3CYP2D6CYP2C19 | |
| SCHEMBL30915258 | 0.80 | AKT1 (0.50) | NR1D1LMNANR1H3CYP2D6CYP2C19 | |
| SCHEMBL7562431 | 0.78 | AKT1 (0.49) | NR1D1LMNANR1H3CYP2D6CYP2C19 | |
| SCHEMBL13014193 | 0.78 | NR1D1 (0.66) | NR1D1ALDH1A1LMNANR1H3CRHBP | |
| SCHEMBL13014185 | 0.78 | NR1D1 (0.66) | NR1D1ALDH1A1LMNANR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | KATHOLIEKE UNIVERSITET LEUVEN (BE) | 2022-08-23 | — | — | US | disclosed |
| EP-3212610-B1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | UNIV LEUVEN KATH (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | US | disclosed |
| EP-3212610-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | Katholieke Universiteit Leuven (BE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016065435-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | H1-3, H1-0, H1-2 | ITGA4 1426/4885ITGB7 1903/4885NR1D1 3515/4885 |
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | H1-3, H1-0, H1-2 | ITGA4 1409/4885ITGB7 1887/4885NR1D1 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.