Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716530 | 0.90 | ERAP1 (0.47) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL17716548 | 0.79 | ERAP1 (0.50) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL17717150 | 0.75 | ATM (0.48) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL17716531 | 0.72 | ERAP1 (0.38) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2000840 | 0.72 | SRC (0.63) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL17716539 | 0.71 | ERAP1 (0.38) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30099332 | 0.69 | ERAP1 (0.41) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL12521745 | 0.68 | RXFP1 (0.50) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL13869289 | 0.68 | ALDH1A1 (0.72) | ERAP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL17716551 | 0.67 | SRC (0.57) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION | 2020-06-18 | — | — | US | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | MPI, TIPRL, BAZ1A | ERAP1 3627/4885ALDH1A1 2490/4885KDM4E 4205/4885 |
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | ZYX, MPI, BAZ1A | ERAP1 3604/4885ALDH1A1 2947/4885KDM4E 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.