Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RARB | P10826 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2039843 | 0.98 | PKM (0.67) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL7595951 | 0.94 | RARB (0.69) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL7401721 | 0.94 | TP53 (0.69) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL1798003 | 0.92 | TP53 (0.72) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL6838614 | 0.92 | PKM (0.69) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL23986236 | 0.90 | PKM (0.57) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL28708015 | 0.90 | PKM (0.57) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL1952122 | 0.90 | TP53 (0.79) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL118037 | 0.90 | PKM (0.77) | PKMTSHRTP53PLA2G4BALDH1A1 | |
| SCHEMBL209561 | 0.88 | TP53 (0.82) | PKMTSHRTP53PLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371808-A1 | Process for preparing dronedarone | Ratiopharm GmbH (DE) | 2011-10-05 | — | — | EP | claimed |
| CN-119823069-A | Inhibitor for improving rheumatoid arthritis by targeting C3aR1 and application thereof | 安徽省立医院(中国科学技术大学附属第一医院) | 2025-04-15 | — | — | CN | disclosed |
| CN-114599362-B | Application of phenylquinolinone and flavonoid derivatives in preparation of medicines for treating neuropathic pain | 杭州百诚医药科技股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-118680931-A | Use of phenylquinolinone and flavonoid derivatives for treating neuropathic pain | 杭州百诚医药科技股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HANGZHOU BIO-SINCERITY PHARMA-TECH CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HANGZHOU BIO-SINCERITY PHARMA-TECH CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-4046638-A1 | USE OF PHENYLQUINOLINONES AND FLAVONOID DERIVATIVES FOR TREATING NEUROPATHIC PAIN | Hangzhou Bio-Sincerity Pharma-tech Co., Ltd. (CN) | 2022-08-24 | — | — | EP | disclosed |
| CN-114599362-A | Use of phenylquinolinone and flavonoid derivatives for treating neuropathic pain | 杭州百诚医药科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| WO-2021072642-A1 | USE OF PHENYLQUINOLINONES AND FLAVONOID DERIVATIVES FOR TREATING NEUROPATHIC PAIN | 杭州百诚医药科技股份有限公司 | 2021-04-22 | — | — | WO | disclosed |
| WO-2021072642-A1 | USE OF PHENYLQUINOLINONES AND FLAVONOID DERIVATIVES FOR TREATING NEUROPATHIC PAIN | 杭州百诚医药科技股份有限公司 | 2021-04-22 | — | — | WO | disclosed |
| US-5631268-A | ANTIALLERGENS, 5HT2 RECEPTOR ANTAGONISTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5602147-A | Piperidinyl thiacyclic derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5596003-A | Piperidinyl thiacyclic derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5541200-A | Piperidinyl thiacyclic derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5476861-A | Piperidinyl thiacyclic derivatives | MERRELL DOW PHARMACEURICALS INC. (US) | 1995-12-19 | — | — | US | disclosed |
| EP-0626968-A4 | — | — | 1995-01-04 | — | — | EP | disclosed |
| EP-0626968-A1 | PIPERIDINYL THIACYCLIC DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5371093-A | Piperidinyl thiacyclic derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| WO-1993016081-A1 | PIPERIDINYL THIACYCLIC DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| US-4861897-A | 2-Aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HRH4, HRH2, HRH1 | PKM 1419/4885TSHR 3422/4885TP53 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.